Angiostatins

Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.

Also Known As:

Angiostatin

Pharmalogical Action Categories:

Angiogenesis Inhibitors
Antineoplastic Agents

Enzymes and Coenzymes: 1
- Enzyme Precursors: 734
  - Plasminogen: 2831
    - Angiostatins: 462
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Angiogenic Proteins: 410
      - Angiostatic Proteins: 9
        Angiostatins: 462
  - Blood Proteins: 12679
    - Serum Globulins: 555
      - Beta-Globulins: 159
        Plasminogen: 2831
        Angiostatins: 462
  - Globulins: 3119
    - Serum Globulins: 555
      - Beta-Globulins: 159
        Plasminogen: 2831
        Angiostatins: 462
  - Protein Precursors: 37
    - Enzyme Precursors: 734
      - Plasminogen: 2831
        Angiostatins: 462
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Angiogenic Proteins: 410
      - Angiostatic Proteins: 9
        Angiostatins: 462
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Angiogenic Proteins: 410
    - Angiostatic Proteins: 9
      - Angiostatins: 462

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